Article ID Journal Published Year Pages File Type
10564902 Current Opinion in Chemical Biology 2013 7 Pages PDF
Abstract
► Not all chelators are the same: more than metal sequestration and elimination. ► Metal chelates can redistribute metals across biological membranes. ► Metal-chelating fragments provide leads for metalloenzyme inhibition. ► Metal chelation can enhance metal reactivity and thus cytotoxicity. ► Prochelators provide site-activated metal chelation and passivation.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
Authors
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