| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10564905 | Current Opinion in Chemical Biology | 2013 | 8 Pages |
Abstract
⺠The rates of water exchange in lanthanide complexes is often overlooked in the design of new imaging agents. ⺠There exists an optimal water exchange rate for T1-based agents, T2 line-broadening agents (i.e., resulting from chemical exchange), and paramagnetic CEST agents. ⺠The optimal water exchange rate for each class of imaging agent varies over several orders of magnitude. ⺠Lanthanide complexes have been reported that have water exchange rates that vary by nearly six orders of magnitude, from 2 ns to 1 ms.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
A. Dean Sherry, Yunkou Wu,