Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10564908 | Current Opinion in Chemical Biology | 2013 | 7 Pages |
Abstract
⺠The irreversible inactivation of protein targets by metal complexes is described. ⺠The article summaries catalysts that hydrolyze or oxidize proteins. ⺠Cyclen-based catalysts that selectively hydrolyze peptides and proteins are described. ⺠Catalysts that generate reactive oxygen species are important for protein inactivation. ⺠Metal-based oxidants are potent and selective agents for protein inactivation.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Jai Prakash, Jeremy J Kodanko,