| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10564918 | Current Opinion in Chemical Biology | 2013 | 8 Pages |
Abstract
⺠Halogenated natural products are diverse in structure, activity, and biosynthesis. ⺠Halogenases can show high regioselectivity that is often difficult to achieve synthetically. ⺠Chlorine and bromine can be installed at a wide range of chemical functionalities. ⺠Developing halogenases through enzyme engineering is an emerging area of study. ⺠Enzymes acting late in biosynthesis hold intriguing potential for synthesis.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Duncan RM Smith, Sabine Grüschow, Rebecca JM Goss,