Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10564958 | Current Opinion in Chemical Biology | 2013 | 8 Pages |
Abstract
- Drug discovery is time-consuming and expensive in part due to unexpected side-effects.
- Identification of cellular targets of drug candidates is important to address this issue.
- In situ proteome profiling using small molecule probes can identify potential cellular targets of bioactive compounds.
- Both non-covalent and covalent drugs are applicable.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Ying Su, Jingyan Ge, Biwei Zhu, Yu-Guo Zheng, Qing Zhu, Shao Q Yao,