Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10564970 | Current Opinion in Chemical Biology | 2013 | 6 Pages |
Abstract
- SIMS is the predominant imaging mass spectrometry (IMS) technique for single-cell MS imaging.
- SIMS at subcellular spatial resolution has led to new biological observations.
- Sensitivity is the 'new challenge' limiting MALDI spatial resolution.
- MALDI is a potential platform for proteomics-based single-cell IMS.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Melissa K Passarelli, Andrew G Ewing,