Article ID Journal Published Year Pages File Type
10565366 Current Opinion in Chemical Biology 2013 5 Pages PDF
Abstract

- Tropolones are bioactive natural products produced by plants, fungi and bacteria.
- Tropolones are biosynthesised by ring expansion of alkylated aromatic rings.
- Tropolones are derived v*ia polyketide, alkaloid, terpene and shikimate pathways.
- Tropolone biosynthesis in fungi is understood at a molecular level, but their biosynthesis in plants and bacteria is only understood v*ia labelling studies.
- Significant opportunity exists for more detailed studies of plant and bacterial tropolone biosynthesis and for metabolic engineering in fungi.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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