| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10565387 | Current Opinion in Chemical Biology | 2013 | 8 Pages |
Abstract
- The single-molecule approach yields exciting insights for many biomolecular applications.
- There are significant challenges to achieve main-stream single-molecule measurements.
- New labelling chemistries enable multiple tagged molecules in vitro and in live cells.
- Single-molecule pull-down expands the toolbox complementing co-immunoprecipitation.
- Breaking the single-molecule concentration barrier is within reach.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Dina Grohmann, Finn Werner, Philip Tinnefeld,