| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10569614 | Coordination Chemistry Reviews | 2013 | 23 Pages |
Abstract
⺠The Cupin fold provides metal binding motif plasticity. ⺠The 2-His binding motif offers a platform for halogenations. ⺠The 3-His binding motif affects the substrate ligation mode and reactivity. ⺠The 3-His-1 Carboxylate Motif shows remarkable metal ion promiscuity. ⺠Outer shell residues impact metal center stability and catalysis.
Keywords
ARDGentisate 1,2-dioxygenaseSDOQDOCS2FLAAcAcMCDEXAFSADOPDBα-KGNRPDFTXASα-ketoglutarateindEPRElectron paramagnetic resonanceDioxygenasecysteine dioxygenaseMagnetic circular dichroismcircular dichroismStructure–function relationshipsX-ray absorption spectroscopyExtended X-ray absorption fine structure spectroscopyDioxygen activationDensity functional theoryCDOHomogentisate 1,2-dioxygenaseProtein Data BankNonribosomal peptideEnzyme catalysis
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Daniela Buongiorno, Grit D. Straganz,