Article ID Journal Published Year Pages File Type
10572647 Inorganica Chimica Acta 2011 7 Pages PDF
Abstract
► New Ni(II) thiosemicarbazone complexes have been synthesized and characterized by analytical, and X-ray crystallography. ► They were subjected to test their DNA topoisomerase II inhibition efficiency. ► The complex [Ni(Nap-mtsc)(PPh3)] (3) showed 95% inhibition which was more potent than the activity of conventional standard Nalidixic acid.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
Topoisomerase II inhibition activity of new square planar Ni(II) complexes containing N-substituted thiosemicarbazones: Synthesis, spectroscopy, X-ray crystallography and electrochemical characterization
Authors
, , , , , , , ,