Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10572697 | Journal of Fluorine Chemistry | 2011 | 4 Pages |
Abstract
â¶ Trifluoromethionine is a promising lead for amebiasis. â¶ Trifluoromethionine is a probe to elucidate the biochemistry of methionine residues in proteins. â¶ Trifluoromethionine is synthesized by direct reductive trifluoromethylation of homocystine. â¶ This method is robust and can be perform at a large scale. â¶ This is the first example of reductive fluoroalkylation of disulfides under the Birch condition.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Hiroyuki Yasui, Takeshi Yamamoto, Etsuko Tokunaga, Norio Shibata,