Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10572837 | Journal of Fluorine Chemistry | 2005 | 8 Pages |
Abstract
In an effort to prepare new fluorine-containing compounds, which are active against HIV, several chemical modifications of a series of benzoxazole and 1,2,4-oxadiazole-CF2CHOHAr derivatives were carried out. The products (9-30) which all have one or two CF2 groups were tested for activity against HIV-1; they were devoid of significant activity, one of them being cytotoxic.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Maurice Medebielle, Samia Ait-Mohand, Conrad Burkhloder, William R. Jr., Géraldine Laumond, Anne-Marie Aubertin,