| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10572866 | Journal of Fluorine Chemistry | 2005 | 13 Pages |
Abstract
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation is described. In particular, the electrophilic alkylation of enolates with a trifluoromethyl group was proceeded with highly diastereofacial selectivity based on the steric and/or electrostatic effect of substituent with strong electron withdrawing.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Kenji Tamura, Takashi Yamazaki, Tomoya Kitazume, Toshio Kubota,