Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10573949 | Journal of Inorganic Biochemistry | 2011 | 8 Pages |
Abstract
Copper(II) complexes with planar heterocyclic bases are prepared. The DNA cleavage experiments show singlet oxygen as the reactive species. The cytotoxicity of the complexes against HeLa cancer cell evaluated and the HeLa cell died through an apoptosis process induced by complexes which indicates that the complexes 1 and 2 are promising drugs for cancer.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Gong-Jun Chen, Xin Qiao, Pei-Qi Qiao, Guang-Jun Xu, Jing-Yuan Xu, Jin-Lei Tian, Wen Gu, Xin Liu, Shi-Ping Yan,