Article ID Journal Published Year Pages File Type
10573957 Journal of Inorganic Biochemistry 2011 6 Pages PDF
Abstract
Radical generation from H2O2/HCO3-/Cu(II) complexes was evaluated. Cu(II)-imine complexes produced low levels of reactive species in vitro, but are able to be uptake by mammalian cell causing its death, whereas Cu(II)-Gly-derived complexes and free Cu(II) ion, produced oxygen-derived radicals in significantly larger amounts in vitro but not being incorporated by cell.
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Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
Radical production by hydrogen peroxide/bicarbonate and copper uptake in mammalian cells: Modulation by Cu(II) complexes
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