| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10573962 | Journal of Inorganic Biochemistry | 2011 | 8 Pages |
Abstract
In contrast to their dichlorido counterparts, new RuII-arene complexes with carbohydrate-derived phosphite and biscarboxylato co-ligands resist hydrolysis and do not exhibit significant reactivity towards biomolecules, such as cysteine, methionine, ubiquitin or the DNA model 5â²-GMP. This causes important changes in the tumor-inhibiting potency of the compounds.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Muhammad Hanif, Samuel M. Meier, Wolfgang Kandioller, Anna Bytzek, Michaela Hejl, Christian G. Hartinger, Alexey A. Nazarov, Vladimir B. Arion, Michael A. Jakupec, Paul J. Dyson, Bernhard K. Keppler,