Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10573968 | Journal of Inorganic Biochemistry | 2011 | 7 Pages |
Abstract
The most likely antimalarial mechanism for complex [Au(CQ)(PPh3)]PF6 is the heme aggregation inhibition; the high activities observed against resistant parasites are probably due to the structural modification of CQ introduced by the presence of the gold-triphenylphosphine fragment, together with the enhanced lipophilic character.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Maribel Navarro, William Castro, Alberto MartÃnez, Roberto A. Sánchez Delgado,