Article ID Journal Published Year Pages File Type
10574022 Journal of Inorganic Biochemistry 2005 10 Pages PDF
Abstract
The reaction between nitrite and hemoglobin has been studied for over a century. However, recent evidence indicating nitrite is a latent vasodilatory agent that can be activated by its reaction with deoxyhemoglobin has led to renewed interest in this reaction. In this review we survey, in the context of our own recent studies, the chemical reactivity of nitrite with oxyhemoglobin, deoxyhemoglobin and methemoglobin, and place these reactions in both a physiological and pharmacological/therapeutic context.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
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