| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10574061 | Journal of Inorganic Biochemistry | 2005 | 6 Pages |
Abstract
Ni(II) complexes of ortho-naphthaquinone thiosemicarbazone and semicarbazone were synthesized and spectroscopically characterized. The X-ray crystal structure of both the complexes describe a distorted octahedral coordination with two tridentate mono-deprotonated ligands. In vitro anticancer studies on MCF-7 human breast cancer cells reveal that the semicarbazone derivative along with its nickel complex is more active in the inhibition of cell proliferation than the thiosemicarbazone analogue.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Zahra Afrasiabi, Ekk Sinn, Weisheng Lin, Yinfa Ma, Charles Campana, Subhash Padhye,