Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10579374 | Tetrahedron: Asymmetry | 2013 | 7 Pages |
Abstract
An organocatalytic cascade Michael/Michael reaction between curcumins and 2-arylidene-1,3-indandiones has been studied. Prolinol, chiral thiourea-tertiary amines, and cinchona alkaloids were evaluated as catalysts. Quinine was identified as the best catalyst for the transformation. Multicyclic spiro-1,3-indandiones were prepared in moderate to excellent yields, diastereoselectivities, and enantioselectivities.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Nian-hua Luo, Xiang Sun, Wen-tao Wei, Xue-jing Zhang, Ming Yan,