| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10579554 | Tetrahedron: Asymmetry | 2010 | 5 Pages |
Abstract
Thiophosphoramide 5d was found to be an effective organocatalyst for the enantioselective Michael reaction of problematic acetone to various hydroxymethyl nitrostyrenes, affording the multisubstituted tetrahydropyrans with three stereogenic centers. The Michael addition products generated were obtained as a single diastereomer with enantioselectivities ranging from 46% to 74% ee.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Yang Wu, Aidang Lu, Yunfeng Liu, Xiaolei Yu, Youming Wang, Guiping Wu, Haibin Song, Zhenghong Zhou, Chuchi Tang,