| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10580343 | Tetrahedron: Asymmetry | 2006 | 8 Pages |
Abstract
(6R,7S,8aR)- and (6S,7R,8aR)-8a-tert-butyldimethylsilyloxymethyl-6,7-dihydroxy-indolizidin-3-ones 14 and 15 were synthesized from bicyclic silyloxypyrrole 2 by the selective formation of a quaternary stereogenic centre and a ring-closing metathesis as the main steps. They were converted into new polyhydroxyindolizidines 20 and 21 with high diastereoselectivity.
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Authors
Nicole Langlois, Bao Khanh Le Nguyen, Pascal Retailleau, Céline Tarnus, Emmanuel Salomon,