Article ID Journal Published Year Pages File Type
10582211 Bioorganic Chemistry 2005 10 Pages PDF
Abstract
Transfer of the γ-phosphoryl group from ATP to aminoglycoside antibiotics by aminoglycoside 3′-phosphotransferases is one of the most important reactions for manifestation of bacterial resistance to this class of antibiotics. This review article surveys the latest structural and mechanistic findings with these enzymes.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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