| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10582835 | Bioorganic Chemistry | 2005 | 13 Pages |
Abstract
A new asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens has been found. Although alcohols are not the natural substrates for this enzyme, a high R enantioselectivity was observed. Stereochemical studies showed that variations in substrate structure lead to strong variations in enantioselectivity. The highest enantioselectivities are obtained when the β-carbon of the secondary alcohol is tertiary or quaternary.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nikos S. Hatzakis, Ioulia Smonou,