Anti-growth effect of a novel trans-dichloridobis[2-(2-hydroxyethyl)pyridine]platinum (II) complex via induction of apoptosis on breast cancer cell lines

Article ID	Journal	Published Year	Pages	File Type
10583527	Bioorganic & Medicinal Chemistry	2015	26 Pages	PDF

Keywords

IC90 RIPA PARP FASLG RPMI Bcl-2 RT-PCR HRP IC50 ABS 7-AAD RTCA HCl Platinum (II) complex PBS 7-amino-actinomycin D cDNA DMSO Complementary DNA DNA MTT SDS–PAGE adenosine-5′-triphosphate ATP deoxyribonucleic acid ribonucleic acid RNA hydrochloric acid Sodium dodecyl sulfate polyacrylamide gel electrophoresis standard deviation Bax BIK Real-time cell analyzer Absorbance Apoptosis Dimethyl sulfoxide Breast cancer Hrk Cytotoxicity radioimmunoprecipitation assay cell index Fas Ligand Phosphate buffered saline B-cell lymphoma 2 Roswell Park Memorial Institute medium Real time polymerase chain reaction Horseradish peroxidase BCL2-associated X protein Propidium iodide poly (ADP-ribose) polymerase Calcein AM

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Anti-growth effect of a novel trans-dichloridobis[2-(2-hydroxyethyl)pyridine]platinum (II) complex via induction of apoptosis on breast cancer cell lines

Authors

Arzu Yilmaztepe Oral, Buse Cevatemre, Mehmet Sarimahmut, Ceyda Icsel, Veysel Turan Yilmaz, Engin Ulukaya,