| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588303 | Bioorganic & Medicinal Chemistry | 2011 | 6 Pages |
Abstract
4-Amino-2-phenylquinazolines were designed as bioisosteres of 3-arylisoquinolinamines that were energy minimized to provide stable conformers. The 2-phenyl ring of 4-amino-2-phenylquinazolines was parallel to the quinazoline ring and improved their DNA intercalation ability in the DNA-topo I complex.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thanh Nguyen Le, Su Hui Yang, Daulat Bikram Khadka, Hue Thi My Van, Suk Hee Cho, Youngjoo Kwon, Eung-Seok Lee, Kyung-Tae Lee, Won-Jea Cho,