| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10597383 | Carbohydrate Polymers | 2012 | 7 Pages |
Abstract
⺠Chemical sulfation of polysaccharides may result in molecules having antithrombotic effect. ⺠Citrus pectin (CP) is a widely available polysaccharide in nature. ⺠Sulfated polysaccharides based on CP have anticoagulant and antithrombotic effects. ⺠Sulfated polysaccharides based on CP inhibit α-thrombin in a serpin-dependent way. ⺠Sulfation pattern affect the anticoagulant and antithrombotic effects.
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Authors
Nadiezda C. Maas, Ana Helena P. Gracher, Guilherme L. Sassaki, Philip A.J. Gorin, Marcello Iacomini, Thales R. Cipriani,