| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10597385 | Carbohydrate Polymers | 2012 | 7 Pages |
Abstract
⺠Amino groups of chitosan were treated with glycidyltrimethylammonium chloride. ⺠Each modified unit contained quaternary and secondary amino groups. ⺠The polymer was soluble in the whole pH range and formed stable polyplexes. ⺠The polymer revealed relatively low cytotoxicity and high transfection efficacy. ⺠The modified chitosans are suitable for delivery of plasmid DNA and siRNA.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Evgeny Faizuloev, Anna Marova, Alexandra Nikonova, Irina Volkova, Marina Gorshkova, Vladimir Izumrudov,