Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10597700 | Carbohydrate Polymers | 2012 | 9 Pages |
Abstract
⺠Synthesis of CM-SPION for targeting APCs including macrophages. ⺠The interaction between the mannose ligand tethered on CM-SPION and mannose receptors on APCs. ⺠The in vitro and in vivo toxicities of CM-SPION were evaluated. ⺠The in vivo uptake of CM-SPION in LNs was tracked by MRI after subcutaneous injection in a rat model. ⺠Pre-dominant accumulation of CM-SPION in the popliteal LN.
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Authors
Hieu Vu-Quang, Muthunarayanan Muthiah, You-Kyoung Kim, Chong-Su Cho, Ran Namgung, Won Jong Kim, Joon Haeng Rhee, Sang Hyeon Kang, Soo Youn Jun, Yun-Jaie Choi, Yong Yeon Jeong, In-Kyu Park,