Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10601599 | Carbohydrate Polymers | 2013 | 10 Pages |
Abstract
⺠Galactosylated chitosan-polycaprolactone is synthesized for delivery of curcumin. ⺠Initial load of curcumin in the resulting nanoparticles reaches around 6%. ⺠Curcumin release from nanoparticles is controlled by polycaprolactone component. ⺠Nanoparticles have hepatocyte-targeted specificity toward HepG2 cells. ⺠Bioavailability of curcumin can be greatly improved using these nanoparticles.
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Authors
Nuo Zhou, Xiaoli Zan, Zheng Wang, Hua Wu, Dengke Yin, Chunyan Liao, Ying Wan,