| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10601659 | Carbohydrate Polymers | 2013 | 8 Pages |
Abstract
⺠Chitosan compared to other shielding materials was exploited for shielding PLA NPs. ⺠The shielding effect on particles zeta potential and hydrophilicity was studied. ⺠The outcome of protection on NPs pharmacokinetics and biodistribution was examined. ⺠Both chitosan and polysorbate-coated NPs exhibited comparable hydrophilic characters. ⺠In vivo uptake in RES was inhibited with chitosan-coated NPs.
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Authors
Rania A.H. Ishak, Gehanne A.S. Awad, Noha M. Zaki, Abd El-Hamid A. El-Shamy, Nahed D. Mortada,