Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10601839 | Carbohydrate Polymers | 2013 | 10 Pages |
Abstract
⺠Chitosan containing pyridinium moiety was synthesized as a model DNA vector. ⺠Nanopolyplex based on chitosan derivative ionically bonded to DNA was obtained. ⺠Transfection efficiency depended on MW, quaternary ammonium type and N/P ratio. ⺠Enhancement in transfection efficiency and reduction of cytotoxicity was achieved.
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Authors
Warayuth Sajomsang, Pattarapond Gonil, Uracha Rungsardthong Ruktanonchai, Maleenart Petchsangsai, Praneet Opanasopit, Satit Puttipipatkhachorn,