Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10601843 | Carbohydrate Polymers | 2013 | 8 Pages |
Abstract
⺠Two salt out salts (NaT and NaC) were added to the MC-PEG solution to reduce the gelation temperature close to physiological temperature. ⺠UV-vis spectroscopy, viscometry and rheometry were used to measure the gelation temperature of all solutions. ⺠The surface topography and cross-sectional structure of the freeze-dried samples of hydrogels were examined. ⺠In vitro drug release studies showed that drug release time increased from 6 to 9 h by only changing the salt from NaT to NaC. ⺠Release of the drug is correlated with the gel morphology.
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Authors
Mrinal Kanti Bain, Dipanwita Maity, Biplab Bhowmick, Dibyendu Mondal, Md. Masud Rahaman Mollick, Gunjan Sarkar, Manas Bhowmik, Dipak Rana, Dipankar Chattopadhyay,