| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10601893 | Carbohydrate Polymers | 2012 | 7 Pages |
Abstract
⺠We prepared a new self-gelling aldehyde-functionalized chitosan that can form gels without the addition of crosslinking agents. ⺠The highly porous self-crosslinked gels allowed for more than 400% of water uptake. ⺠The rheological properties of these gels were directly influenced by the concentration of the aldehyde-functionalized chitosan. ⺠The gels were able to release molecules with different sizes following a near zero-order profile. ⺠The increase in the crosslinking density in these gels at higher pH retarded the drug release.
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Authors
Eduardo P. Azevedo, Vijay Kumar,