Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10601925 | Carbohydrate Polymers | 2012 | 5 Pages |
Abstract
⺠A polysaccharide (PTP) was isolated from the roots of Polygala tenuifolia. ⺠PTP was effective on inhibiting the proliferation of SKOV3 cells in a concentration-dependent manner. ⺠PTP caused a rapid depletion of intracellular GSH in SKOV3 cells. ⺠PTP caused the accumulation of intracellular ROS in SKOV3 cells. ⺠PTP administration could significantly inhibit tumor growth in nude mice.
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Authors
Tao Xin, Fubin Zhang, Qiuying Jiang, Chunhong Chen, Dayong Huang, Yanju Li, Weixi Shen, Yinghua Jin,