Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10601930 | Carbohydrate Polymers | 2012 | 8 Pages |
Abstract
⺠HMW-HA induced Akt and increased PPARγ in chondrosarcoma cells. ⺠HMW-HA reduced COX-2 and MMPs expression by suppressing MAPKs and NFκB signaling. ⺠Oligo-HA inhibited Akt, and reduced PPARγ in the cells. ⺠Oligo-HA increased COX-2 and MMPs expression via activation of p38 and NFκB.
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Authors
Chi-Ching Chang, Ming-Shium Hsieh, Say-Tsung Liao, Yi-Hsuan Chen, Chao-Wen Cheng, Pai-Tsang Huang, Yung-Feng Lin, Chien-Ho Chen,