| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10602050 | Carbohydrate Polymers | 2012 | 9 Pages |
Abstract
⺠Chitosan (CS)-caseinophosphopeptide (CPP) nanoparticles as a delivery system for epigallocatechin gallate (EGCG) have been developed. ⺠Physical, chemical and biological properties of the nanoparticles were characterized systematically. ⺠Cross-linking CS with peptides reduced the cytotoxicity of CS nanoparticles. ⺠Dose and time dependent cellular internalization of EGCG-loaded CS-CPP nanoparticles was confirmed by green fluorescence inside the Caco-2 cells. ⺠Intestinal permeability of EGCG was significantly enhanced by the CS/CPP nanoparticles.
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Authors
Bing Hu, Yuwen Ting, Xiaoxiong Zeng, Qingrong Huang,