Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602065 | Carbohydrate Polymers | 2012 | 8 Pages |
Abstract
⺠OCMCS was investigated for the mucoadhesion and permeation enhancement at neutral pH. ⺠OCMCS nanoparticles showed high adhesion tendency onto carp intestinal mucosa. ⺠OCMCS nanoparticles promoted FD4 transport through excised carp intestinal mucosa. ⺠The improvement of permeability was further verified via Caco-2 cell monolayer. ⺠Cytotoxicity studies in Caco-2 monolayers verified the safety of the delivery system.
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Organic Chemistry
Authors
Ya Liu, Hui Di Zang, Ming Kong, Fang Kui Ma, Qi Feng Dang, Xiao Jie Cheng, Qiu Xia Ji, Xi Guang Chen,