Article ID Journal Published Year Pages File Type
10602091 Carbohydrate Polymers 2011 9 Pages PDF
Abstract
► Ionic concentration strength and pH on theophylline release evaluated using USP III. ► Ionic concentration strength varied over a range of 0-0.4 M to simulate the GI fed and fasted states. ► DSC hydration results explained the theophylline release from their HPMC matrices. ► Method can be useful in predicting potential ionic effects in fed and fasted states.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Effect of ionic strength and pH of dissolution media on theophylline release from hypromellose matrix tablets-Apparatus USP III, simulated fasted and fed conditions
Authors
, , , ,