Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602179 | Carbohydrate Polymers | 2012 | 9 Pages |
Abstract
⺠Two biocompatible and biodegradable polyampholyte microgels were prepared. ⺠The microgels were pH- and thermo-responsive. ⺠Microgels possessed positive and negative charges at low and high pH, respectively. ⺠The hydrodynamic radii were 190 nm at low pH, 80 nm at neutral pH, to 120 nm at a high pH. ⺠In vitro drug release studies confirmed that the microgels could encapsulate and release a model drug. ⺠They could potentially be used as biocompatible and biodegradable drug carriers.
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Authors
Neha Dhar, Seyedeh Parinaz Akhlaghi, Kam C. Tam,