| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10602244 | Carbohydrate Polymers | 2012 | 8 Pages |
Abstract
⺠Highly branched water-soluble heteropolysaccharides (WSHP) were isolated from Rhizoma panacis Japonici. ⺠WSHP were α-(1 â 4)-d-glucan with side chain residues of mannose and galactose in spherical chain conformation. ⺠WSHP inhibited the growth of Sarcoma 180 tumors implanted in BALB/c mice. ⺠The antitumor effect of WSHP was mediated by potentiation of immune cells and induction of apoptosis in the tumor cells. ⺠WSHP alleviated the short-term side effect of the antitumor drug cisplatin during the treatment period.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhiping Huang, Lina Zhang, Xiaobo Duan, Zongquan Liao, Hong Ding, Peter C.K. Cheung,