Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602367 | Carbohydrate Polymers | 2011 | 10 Pages |
Abstract
⺠Low molecular weight heparin-all-trans-retinoid acid (LHR) conjugate was developed. ⺠Studies showed that it was a safe material for intravenous administration. ⺠LHR conjugate could self-assemble to form nanoparticles for loading paclitaxel (PTX). ⺠PTX-loaded LHR nanoparticles displayed enhanced PTX-induced cytotoxicity and an extended circulation of PTX and ATRA.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lin Hou, Ying Fan, Jing Yao, Jianping Zhou, Caocao Li, Zhengjie Fang, Qiang Zhang,