| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10602460 | Carbohydrate Polymers | 2011 | 7 Pages |
Abstract
⺠We applied the nano-polyplexes based gene delivery using water-soluble chitosan and polyethyleneimine (PEI) for therapeutic gene delivery into the osteoblastic-like cell line, MG-63. ⺠The transfection efficiency and cytotoxicity were investigated. ⺠Bone morphogenesis protein (BMP) gene delivery was performed. ⺠Comparing with commercial available system, lipofectamine, the expression of BMP were prolonged. ⺠This study proposes the non-viral vector as a promising approach for bone regeneration though gene therapy.
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Authors
Nattika Saengkrit, Warayuth Sajomsang, Varaporn rakkhithawatthana, Tewin Tencomnao,