| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10602803 | Carbohydrate Polymers | 2012 | 8 Pages |
Abstract
⺠The chitosan nanoparticles significantly increased the permeation of drug through nasal mucosa. ⺠The chitosan nanoparticles improved the parameters of pharmacodynamic studies in depressed rats. ⺠Nose to brain delivery of chitosan nanoparticles was shown by confocal laser scanning microscopy. ⺠The higher drug targeting efficiency and nose to brain direct transport percentage of chitosan nanoparticles suggest better brain targeting efficiency. ⺠The chitosan nanoparticles could be a promising approach for nose to brain delivery of venlafaxine.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shadabul Haque, Shadab Md, Mohammad Fazil, Manish Kumar, Jasjeet Kaur Sahni, Javed Ali, Sanjula Baboota,