Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602859 | Carbohydrate Polymers | 2012 | 7 Pages |
Abstract
⺠Sucrose, Avicel RC591 and Aerosil were chosen as suitable cryoprotectants for freeze drying NLCs. ⺠Taguchi design was successful for optimization of freeze drying conditions of NLCs. ⺠Increasing cryoprotectants concentration increased the particle size of NLCs. ⺠1% Avicel RC591, 24 h freezing at â70 °C and 48 h sublimation were proper for lyophilization the NLCs. ⺠Avicel RC591 a mixed co-processed carbohydrate polymer is promising in lyophilization of NLCs.
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Authors
Jaleh Varshosaz, Sharareh Eskandari, Majid Tabbakhian,