Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602914 | Carbohydrate Polymers | 2012 | 10 Pages |
Abstract
⺠Thermal acid degradation of hyaluronan yields unwanted degradation byproducts (DB). ⺠The major DB were identified as derivatives of furan and cylopentanone. ⺠Some of the DB were found to be toxic for cell growth. ⺠The unwanted DB can be removed from hyaluronan fragments by ultrafiltration.
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Authors
Daniela Å mejkalová, Martina Hermannová, Radovan Buffa, Dagmar ÄožÃková, Lucie ViÅ¡tejnová, Zuzana Matulková, Jaroslav Hrabica, VladimÃr Velebný,