Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10602963 | Carbohydrate Polymers | 2012 | 9 Pages |
Abstract
⺠Synthesis of a new derivative of chitosan, oligomeric chitosan linked to all trans retinoic acid, and evaluation of micelle formation. ⺠Micelles show low CAC value, colloidal stability, lack of cytotoxicity, nano-range particle size and positive charge. ⺠Loading all trans retinoic acid as hydrophobic drug in the micelles shows a good loading efficiency and sustained release capacity in which make the micelles a good candidate for drug delivery.
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Authors
Ali Fattahi, Mohammad-Ali Golozar, Jaleh Varshosaz, Hamid Mirmohammad Sadeghi, Mohammadhossein Fathi,