Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10603013 | Carbohydrate Polymers | 2012 | 5 Pages |
Abstract
⺠We examined the preventive effects of chitin nanofibrils in a model of acute ulcerative colitis. ⺠Chitin nanofibrils improved clinical symptoms and suppressed ulcerative colitis. ⺠Chitin nanofibrils suppressed myeloperoxidase activation in the colon and decreased serum interleukin-6 concentrations. ⺠Chitin nanofibrils have potential as a functional substance for inflammatory bowel disease patients.
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Authors
Kazuo Azuma, Tomohiro Osaki, Takashi Wakuda, Shinsuke Ifuku, Hiroyuki Saimoto, Takeshi Tsuka, Tomohiro Imagawa, Yoshiharu Okamoto, Saburo Minami,