Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10603748 | Carbohydrate Polymers | 2013 | 7 Pages |
Abstract
⺠Doxorubicin loaded acetylated fucoidan (AcFu) nanoparticles were investigated for immunochemotherapy in cancer treatment. ⺠The nanoparticles exhibited first-order drug release behavior for 5 days. ⺠AcFu treated Raw264.7 macrophages overexpressed various anti-tumor cytokines. ⺠The nanoparticles resist to multidrug resistance characteristics of cancer cells. ⺠The nanoparticles have a promising potential for one-step immunochemotherapy.
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Authors
Kun Woo Lee, Dooyong Jeong, Kun Na,