Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10603860 | Carbohydrate Polymers | 2012 | 10 Pages |
Abstract
⺠β-Cyclodextrin enhanced warfarin solubility (solubilizing power; 1.39 Ã 10â3 mM). ⺠Warfarin-β-cyclodextrin complex was well incorporated into chitosan nanoparticles. ⺠Chitosan nanoparticles were found to be spherical with narrow size distribution. ⺠Release of complex from carrier showed an initial burst then a slow constant phase. ⺠Chitosan/cyclodextrin carrier offered controlled permeation of warfarin ex vivo.
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Authors
Safaa K.H. Khalil, Gina S. El-Feky, Sally T. El-Banna, Wafaa A. Khalil,